Small molecule · CNS / Neurology
Ubrogepant
UbrelvySmall moleculeCGRP receptor antagonist
PubChem CID 68748835 · 3D model
Drag to rotate. Scroll or pinch to zoom.
Blocks a receptor for a nerve signaling molecule (CGRP) that drives the pain and inflammation of a migraine attack.
How it works
During a migraine, the body releases a molecule called CGRP that widens blood vessels around the brain and triggers pain and inflammation signals. Ubrogepant works by plugging into the docking site that CGRP normally attaches to, so the molecule can't deliver its pain-triggering message. Because it doesn't constrict blood vessels the way older migraine medicines do, it may be an option for people who can't take those drugs.
What it’s used for
Used to treat a migraine attack once it starts, not to prevent migraines from happening in the first place.
- Mechanism
- CGRP receptor antagonist
- Drug class
- Small molecule
- Therapeutic area
- CNS / Neurology