ligand.
Structural drug index · 238 drugs

Every medicine is a fit.

Explore 238 real drugs, and see exactly where many of them grip their target. Every structure comes from a public scientific record.

TryAdvilLipitorHumiradiabetes

Imatinib seated in human ABL kinase, with its contacts marked in coral.
Imatinib, dockedin human ABL kinase · RCSB 2HYY
CONTACTSGlu286Thr315Met318Ile360His361Asp381
drugs
238
small molecules
156
biologics
71
combinations
11
shown in their target so far
17
How a drug fits

Shape, target, contact.

  1. 01

    Every drug has a shape

    A real 3D structure, from PubChem or the Protein Data Bank, never drawn by hand.

  2. 02

    It's made for a target

    Usually a protein (in your body, or in a virus or bacterium) with a site the drug is shaped to fit.

  3. 03

    Contact holds it in place

    The points where drug and target touch keep it seated. On LIGAND they're marked in coral.

Fits to explore

All 238 drugs →
Molecule of the week

Ubrogepant

Ubrelvy

Blocks a receptor for a nerve signaling molecule (CGRP) that drives the pain and inflammation of a migraine attack.

Open profile

Drugs that changed medicine

All 10 →
  1. 1997 · RituximabThe antibody that opened the era of biologic cancer therapy
  2. 2014 · BlinatumomabThe antibody engineered to physically wire a T cell to its target
  3. 2023 · Exagamglogene autotemcelThe first medicine built by directly editing the human genome

Newly approved

What's new →
FDA approval · Aug 26, 2026
DaraxonrasibRasonque

First-in-class broad RAS(ON) inhibitor approved for metastatic pancreatic cancer.

Read the approval →

Ask Mol about any drug here.

Mol answers from LIGAND's reviewed entries and shows its sources. It lives in the corner of every page.

Where the data comes from

Every structure and fact, sourced and linked.

Each drug page links straight to its records in these public databases, so you can check anything yourself.